Various apprehensions are troubling people about the corona virus vaccine which is wreaking havoc all over the world. In many countries of the European Union including America, Britain Coronavirus Vaccine The news of blood clots in the body of people after taking it has created more panic. However, experts have claimed that the benefits of this vaccine are many times more than the disadvantages. For this, Saint-Ren Pasricha, Division Head of the Department of Population Health and Immunity at the Walter and Eliza Hall Institute, and Professor Paul
Should I get the AstraZeneca vaccine?
He wrote in The Conversation that as specialists in blood diseases, we care for many patients who have had prior blood clots or who take blood-thinning medications. They often ask: “Should I get the AstraZeneca vaccine?” The answer is usually a definite “yes”. The blood clots we’ve seen after the AstraZeneca vaccine are very different from those caused by vein thrombosis or pulmonary embolism, or heart attacks and strokes.
People with a history of these types of conditions do not appear to be at any risk from getting the AstraZeneca vaccine. In fact, people in this group may be at higher risk from COVID-19, so vaccination should not be delayed.
First, how do blood clots form?
Blood flows through the vessels of our body as a liquid, carrying oxygen, nutrients, proteins and immune cells to every organ. But if we get injured or have surgery, our body needs to stop the bleeding from the wound. Our blood has components that work to convert it from a liquid to a semi-solid clot in a matter of seconds. At the first sign of damage, the smallest of the blood cells – platelets – stick to the wall of the damaged blood vessel, and together with the damaged wall, the clotting proteins that have accumulated there stop the bleeding from the wound. Huh.
how clots form in veins
Sometimes the natural process of clotting in the blood and the anticoagulant process becomes unbalanced, increasing the risk of blood clots forming in a person’s veins. It can happen in the following people:
- patients with cancer or infection
- pregnant women
- taking the contraceptive pill containing estrogen
- who are unable to walk after surgery or major trauma
- who have inherited such circumstances
In all these cases, an abnormal blood clot can develop in the deep veins of the thigh and groin (thrombosis of the veins), or in the lungs (pulmonary embolism). Also, blood clots are rare in other places – for example, in the veins of the abdomen or brain.
How do artery clots form?
The arteries that supply blood to the heart, brain, and lower limbs can usually become narrowed because of risk factors including smoking, diabetes, and high blood pressure and cholesterol. A clot that forms in these places can obstruct blood flow, which can lead to a heart attack or stroke.
What is TTS?
AstraZeneca vaccine is associated with a rare condition called thrombocytopenia syndrome, or thrombosis with TTS. Cases of this condition have also been reported after the Johnson & Johnson Kovid vaccine, although it is not available in Australia. We now know a lot more about this situation than a few months ago.
TTS is caused by an abnormal immune response, which results in the development of an antibody directed at platelets (blood cells that stop bleeding). This causes platelets to become overactive, which causes blood clots in the body to form in places where we don’t normally see clots, such as the brain or abdomen. Platelets are also consumed in this process, resulting in a reduced number of platelets. Thrombosis refers to clotting, and thrombocytopenia refers to a low platelet count.
Estimated negative impact on 1 person in a lakh
The Australian Technical Advisory Group on Immunization (ATAGI) recently estimated the risk of getting the AstraZeneca vaccine in Australia for people aged 50 and older, with the risk of TTS at 1.6 per 100,000 doses. However, this figure may change as more people have now been given the vaccine. Fortunately, rapid progress has been made in the diagnosis and treatment of TTS. Doctors now know about its symptoms. Most TTS patients in Australia have recovered or are recovering.
Don’t delay getting covid vaccine
There is no evidence that people who have had blood clots in the past or who have an inherited condition, or who take blood thinners or similar medicines, have a higher risk of getting TTS. It is important to remember that people with risk factors for heart attack and stroke, including diabetes and high blood pressure, increase the risk of developing severe COVID-19 when infected. In addition, COVID itself makes the blood more “sticky” and significantly increases the risk of blood clots.
doctors advice to patients
That’s why we advise our patients: Even if you have had deep vein thrombosis, pulmonary embolism, heart attack or stroke before, you are not at risk of TTS from vaccination. You should get vaccinated as soon as you are eligible.